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16 March 2021

AstraZeneca vaccine: World health experts meet to review safety

16 March 2021

The World Health Organisation (WHO) is urging countries to continue using the AstraZeneca Covid-19 vaccine as global medical leaders meet to discuss reports of blood clots.

WHO’s global advisory committee on vaccine safety will hold a meeting on Tuesday, while the European Medicines Agency (EMA) will also meet, with a view to publishing further guidance on Thursday.

Dr Soumya Swaminathan, WHO’s chief scientist, told a media briefing “we do not want people to panic”, as she said no association has been found so far between blood clots and Covid-19 vaccines.

She said the rates at which blood clots have occurred in people who received the AstraZeneca vaccine “are in fact less than what you would expect in the general population”.

A small number of cases of blood clots in people having the jab have been reported in Europe, prompting several European countries including Germany, France, Italy, Spain, Denmark and Norway to halt rollout of the vaccine.

The WHO, the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) and the EMA have all said there is no evidence the jab causes the problems.

An EMA spokesman said “many thousands of people develop blood clots annually in the EU for different reasons”, adding that the incidence in vaccinated people “seems not to be higher than that seen in the general population”.

According to AstraZeneca, about 17 million people in the EU and the UK have received a dose of the vaccine, with fewer than 40 cases of blood clots reported to date.

Peter Openshaw, professor of experimental medicine at Imperial College London, said the decision to pause rollout of the Oxford/AstraZeneca jab could be a “disaster” for Covid-19 vaccine uptake in Europe.

HEALTH Coronavirus (PA Graphics)

Asked what he would say to those in the UK who are booked to receive the vaccine, he told BBC Radio 4’s Today programme: “I really wouldn’t be worried at the present time.

“I think it is very clear that the benefits of being vaccinated at the moment so far outweigh the possible concern over this rather rare type of blood clot.

“It really is a completely one-sided argument statistically that we need to be vaccinating.

“I think it is a disaster for the vaccination uptake in Europe, which is already on slightly unsteady ground in some countries.”

Asked why he thought the temporary suspension of the vaccine had been taken up by so many countries, he said: “I think the committees are probably afraid of not making that decision to pause on the basis that they might be in some way thought culpable if they didn’t, but actually these are such rare events.”

Coronavirus graphic (PA Graphics)

On Monday, Germany’s health minister said the decision to suspend AstraZeneca jabs was “purely precautionary” and was taken on the advice of the country’s vaccine regulator, which called for further investigation into seven cases of clots in the brains people who had been vaccinated.

French President Emmanuel Macron said his country will halt the vaccine until at least Tuesday afternoon.

The Netherlands, the Republic of Ireland, Bulgaria, Iceland and Thailand have already temporarily suspended use of the jab.

In the UK, medical experts have defended the use of the vaccine while Prime Minister Boris Johnson said there was “no reason at all” to stop its rollout.

Scotland’s First Minister Nicola Sturgeon said she would accept the jab “without hesitation”.

Coronavirus graphic (PA Graphics)

Northern Ireland’s chief medical officer Dr Michael McBride also urged people to retain confidence in the jab, as he received his first dose of the AstraZeneca vaccine on Monday.

Mr Johnson said the MRHA was “one of toughest and most experienced regulators in the world”.

“They see no reason at all to discontinue the vaccination programme… for either of the vaccines that we’re currently using,” he said.

Meanwhile, Ms Sturgeon is due to announce further aims for the easing of lockdown measures on hospitality and retail in Scotland on Tuesday.

Stormont ministers will also meet on Tuesday to discuss easing lockdown restrictions.

Decisions are expected to focus on schooling and allowing more outdoor activities for young people.

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