Pope Francis celebrated Christmas Eve mass before an estimated 1,500 people in St Peter’s Basilica on Friday, going ahead with the service despite the resurgence in Covid-19 cases that has prompted a new vaccine mandate for Vatican employees.

A maskless Francis processed down the central aisle of the basilica as the Sistine Chapel choir sang “Noel”, kicking off the Vatican’s Christmas holiday that commemorates the birth of Jesus in a manger in Bethlehem.

In his homily, Francis urged the faithful to focus on the “littleness” of Jesus, and remember that he came into the world poor, without even a proper crib.

“That is where God is, in littleness,” Francis said.

“This is the message: God does not rise up in grandeur, but lowers himself into littleness.

“Littleness is the path that he chose to draw near to us, to touch our hearts, to save us and to bring us back to what really matters.”

The midnight mass actually began at 7.30pm, a nod to the 85-year-old pope’s endurance and a hold-over from last year, when the service had to end before Italy’s nationwide Covid-19 curfew.

No curfew is in place this year, but cases this week have surged even beyond 2020 levels.

For the second day in a row, Italy on Friday set a new pandemic daily record with 50,599 new cases.

Another 141 people died, bringing Italy’s official death toll to 136,386.

The Vatican secretary of state on Thursday imposed a new vaccine mandate on all Vatican staff, extending it to all employees except those who have recovered from coronavirus.

Previously, only employees who dealt with the public directly had to be vaccinated, such as staff at the Vatican Museums and the Swiss Guards, while others could access their offices with regular testing.

The mandate does not apply to the faithful attending mass, but they are required to wear masks.

The faithful attending Friday’s mass, and the priests, bishops and cardinals concelebrating it, all wore masks.

Francis, who is missing part of one lung and had intestinal surgery in July, has largely eschewed masks, even when greeting prelates and the general public.

Francis is believed to have received the third booster shot, as has emeritus Pope Benedict XVI.

Francis has said vaccination is an “act of love” and he has called for wealthier countries to provide the shots to the developing world.