Manchester City blew rivals United away in the second half to advance to the quarter-finals of the Women’s FA Cup with a 4-1 win at the Leigh Sports Village.

United had capitalised on their early dominance to take the lead in the 13th minute when Katie Zelem’s corner sailed all the way into the net untouched at the far post.

City could not make their possession pay before the break but two half-time changes altered the flow of the game as Caroline Weir and Hayley Raso replaced Vicky Losada and Jess Park.

Four minutes after the restart, Raso’s cross was deflected into the path of Lauren Hemp to apply the finish, and 10 minutes later Ellen White pounced on a poor back header from Hannah Blundell to round Mary Earps and fire home.

A minute later, United’s old nemesis Weir – the match winner in the league two weeks ago – struck again, with Earps guilty of a letting a low shot pass through her at the near post.

And City’s victory was assured when two substitutes combined seconds after coming on, with Khadija Shaw on hand to poke home after Earps was unable to hold Julie Blakstad’s shot.

Stunning goals from Katie McCabe and Caitlin Foord highlighted a 4-0 romp for Arsenal at Liverpool.

Foord opened the scoring in the 19th minute, latching on to a fine ball from Rafaelle, but the best was yet to come.

McCabe hit a superb volley to double the lead before Foord turned to strike a third from the edge of the area.

Kim Little added a fourth in the 68th minute after exchanging passes with Foord.

Dagny Brynjarsdottir scored in stoppage time at the end of the first half of extra time as West Ham edged out Reading 1-0, while goals in either half from Kenza Dali and Anna Anvegard saw Everton knock out Charlton with a 2-0 win over the Championship side.

Southampton goalkeeper Kayla Rendell scored a dramatic equaliser in stoppage time of extra time to cancel out Anna Grey’s 109th-minute goal for Ipswich and send their tie to penalties, but the hosts prevailed 4-2 on spot-kicks.

Birmingham needed Louise Quinn’s 78th-minute goal to see off the stiff resistance of Championship side Durham in the north east.

Coventry are through after a 4-2 win away to West Brom. Alanah Mann and Freya Thomas put Coventry in charge before Shannon Stamps pulled one back.

Katie Wilkinson stretched the lead but Leigh Dugmore scored from the spot in the 77th minute after Natalie Haigh saw red, setting up a tense finale before Olivia Fergusson’s 87th-minute goal settled it.