Willie Mullins insists he will be taking nothing for granted in the jump trainers’ title race, despite building up a sizeable lead via an Ayr four-timer which included a crucial Coral Scottish Grand National triumph.

The Closutton powerhouse began the day £4,982 behind Dan Skelton but powered clear at the top of the table after Macdermott’s big-race success was backed up by wins for Sharjah, Chosen Witness and Quai De Bourbon.

“We’ve one hand on it, but there’s £650,000 in prize-money next weekend, so we can’t stop and we have to keep going – we’ll see you at Ffos Las on Monday,” said Mullins, who is bidding to become the first trainer from Ireland to add the British crown since the great Vincent O’Brien did it in successive years in the 1950s.

Tommy’s Oscar (15-2) gave everyone an early reminder that it was not all about just the big three trainers when kicking off proceedings with his 12th career victory in the Scotty Brand Handicap Chase for Ann Hamilton.

Mullins then struck the first significant blow when Sharjah was given a beautiful ride by Paul Townend to land the CPMS Novices’ Champion Handicap Chase at 7-1, securing £25,720 for his team.

The six-time Grade One winner over hurdles was being tried over three miles for the first time and had to shoulder top-weight of 12st, but he cruised through from the rear to hit the front approaching the last and survived a mistake at that obstacle to oblige.

Mullins told Racing TV: “I did say to David Casey ‘enter everything that’s qualified for anything’ and we’re here!

“Coming back to a handicap, he just found travelling much easier than the pace of Grade One races, so it probably felt like a bit of work for him at home just going at that pace, so that was a big help to get him home.

“The logistics of bringing 18 horses over are pretty huge and they don’t let me near that side of things, or else none of them might arrive, but my drivers and people in the office are wonderful, so I’m thankful I don’t have any of those headaches.”

Mullins came closest to grabbing Coral Scottish Champion Hurdle glory when Bialystok was produced for a strong late challenge by Townend, but they had to settle for second best behind Alan King’s Favour And Fortune.

It was still a nice £21,200 boost, with Nicholls saddling Afadil and Rubaud to finish fourth and sixth respectively, with Dan Skelton’s 11-4 favourite L’Eau Du Sud sandwiched in between.

Skelton must have had high hopes of hitting the target with Coco Mademoiselle when she surged ahead between the final two flights in the Jordan Electrics Ltd Seafield Trophy Mares’ Handicap Hurdle.

However, Czech Her Out soon emerged from the chasing pack and went on to score an emphatic victory for Lucinda Russell, leaving Coco Mademoiselle in the runner-up spot and Saylavee third for Mullins.

Macdermott then helped Mullins to take command by getting the better of Surrey Quest in a thrilling finish to the Scottish Grand National, a narrow triumph under the trainer’s nephew Danny which was worth a whopping £112,540 to his connections.

“It’s fantastic and I’m delighted Danny did it,” said Mullins. “Well done Pat Gallagher for letting me bring the horse here and all my other owners, plus David Casey back at home, who plans all this and puts all the entries in.

“I’d say we’ve a bit to go yet, there’s still a lot of prize-money to play for, but we’re in pole position and it looks very good.”

Mullins had lost two of his six runners early on, but the others all did their bit to boost his tally, with Klarc Kent, Ontheropes and Spanish Harlem ending up fourth, fifth and sixth for another £18,580.

Chosen Witness rammed home the advantage when edging out the Skelton-trained Major Fortune for a 16-1 win in the Let Good Times Roll With Stagecoach Novices’ Handicap Hurdle.

Quai De Bourbon then justified odds of 8-11 when galloping on strongly to take the Tennent’s Novices’ Hurdle by six lengths.

There was a minor disappointment for the Mullins team when 11-10 favourite C’est Ta Chance could only manage fourth behind Gordon Elliott’s Jazz De Cotte in the concluding Golf Inn Prestwick Open National Hunt Flat Race but spirits will still have been high on the journey home.

Paddy Power had taken the decision to pay out on a Mullins title triumph before Friday’s card at Ayr and their spokesman Paul Binfield said: “We thought it was all over yesterday, it probably is now.”